3D histology made easy

Clepio Biotech enables quantitative and scalable volumetric analysis of biological tissues with unprecedented resolution and throughput.

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Why Choose Us

High resolution, really

Thanks to our patented autofocus and light-sheet stabilization systems, the entire sample is imaged at high contrast and sub-cellular resolution.

No surprises with large variability in image quality across the sample.

Your sample, entirely

The full sample is imaged at high resolution. You do not have to pre-select regions of interest during imaging, losing time and potentially precious information.

ROIs can be selected during visualization to load high resolution data.

Data analysis, easily

You are not alone with TeraBytes of data. We will help you along the whole processing pipeline with dedicated quantification tools.

With Clepio Biotech, you get real data, not just nice images.

Our Services

Discuss with us your analysis, ship us your sample, then you're done.

We will take care of the entire pipeline, enabling unprecedented applications for preclinical and clinical research.

3D analysis of histological biomarkers

Obtain a full volumetric map of the spatial distribution of up to 3 different biomarkers.

3D pseudo-H&E imaging

Navigate through a full-resolution map of your sample colored with a pseudo-H&E staining.

Quantification of cell distribution

Get a list of the spatial coordinates of selected cell types.

Neuronal activation mapping

Quantify neuronal activation in large samples mapping immediate early genes.

Vasculature tracking

Reconstruct and analyze the complete 3D structure of the vascular network in your samples.

Volumetric drug distribution analysis

Evaluate the spatial reach of pharmacological treatments.

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Interested in getting the full 3D information from you tissue samples?

Get in touch with our team to discover how our unique technology can change your way of doing science.

Get in touch

Recent Blog Posts

2026, July 20

Clepio Hosts the 3D PATH M15 Technical Consortium Meeting

On July 20th, Clepio Biotech welcomed the partners of the European project 3D PATH to its headquarters...

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2026, July 10

Clepio Brings 3D Digital Pathology to ASMN IRCCS Reggio Emilia

Clepio Biotech was pleased to be hosted by ASMN IRCCS Reggio Emilia for a workshop dedicated to...

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2026, June 3

Clepio Biotech at the EIC Summit 2026

CClepio Biotech participated in the European Innovation Council (EIC) Summit 2026 in Brussels...

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2026, May 8

Clepio at AI for Oncology 2026: bringing 3D histology into the AI era

Clepio Biotech participated in the 4th edition of the AI for Oncology and Cancer Research conference in Milan...

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